Disintegration Tester
Disintegration Tester with basket assembly, are used for detecting disintegration of solid in prescriptive conditions.
Used to automatically control the temperature, time and frequency of nacelle back and forth, preset and real time data can be displayed alternately in time.
IQ/OQ documents included free of charge.
It is manufactured in compliance to the USP and EP
For BJ-1
- There are 6 tubes in one basket assembly, auto stops at timing point.
- The bath liquid can achieve an even temperature.
- A MPU is used to automatically control the temperature, time and frequency of nacelle back and forth.
- Timing at will. The preset and real time data can be displayed alternately in time.
- Automation: auto-test, auto-diagnose, auto-alarm.
For BJ-2
- There are 12 tubes in 2 basket assemblies.
- Each test station is driven independently, auto stops at timing point.
- The bath liquid can achieve an even temperature.
- A MPU is used to automatically control the temperature, time and frequency of nacelle back and forth.
- Timing at will. The preset and real time data can be displayed alternately in time.
- Automation: auto-test, auto-diagnose, auto-alarm.
For BJ-3
- There are 18 tubes in 3 basket assembly.
- Each test station is driven independently，auto stops at timing point.
- The bath liquid can achieve an even temperature.
- A MPU is used to automatically control the temperature, time and frequency of nacelle back and forth.
- Timing at will. The preset and real time data can be displayed alternately in time.
- Automation: auto-test, auto-diagnose, auto-alarm.
| Model | BJ-1 | BJ-2 | BJ-3 |
| Testing Station | 1 | 2 | 3 |
| Speed | 30~32 /min | 30~32 /min | 30~32 /min |
| Height of Stroke | 55±1 mm | 55±1 mm | 55±1 mm |
| Timing Range | 1~900 mins | 1~900 mins | 1~900 mins |
| Temperature | Rt~45 °C | Rt~45 °C | Rt~45 °C |
| Accuracy of Temperature | ±0.5 °C | ±0.5 °C | ±0.5 °C |
| Power Supply | 220V/ 50Hz, 110V/ 60Hz | 220V/ 50Hz, 110V/ 60Hz | 220V/ 50Hz, 110V/ 60Hz |
| Power | 600W | 600W | 600W |
| Dimension | 260×300×420 mm | 400×300×420 mm | 540×300×420 mm |
What is Disintegration?
Disintegration is the vitro test which is performed using basket rack assembly to check the rate at which the tablet breaks down into small fragments.
The process in which solid dosage forms when come in contact with fluid breaks down into small granules of fragments which pass through the mesh no #10 or 2.0±0.2 mm leaving behind no solid mass.
Explanation
Disintegration test is performed in vitro means outside the body to check that our tablets or solid dosage form breaks down properly into small fragments in a specified time period.
When we take a solid dosage form it should disintegrate properly inside the body to facilitate the process of drug release.
If we take a solid dosage form which does not disintegrate in the body will not produce the desired pharmacological effect.
The disintegration time can be adjusted using a class of excipients known as disintegrants and super disintegrants.
These disintegrants or super disintegrants break the bondings in solid dosage forms and facilitate the drug release.
What is disintegration time?
Disintegration time is the time required for a dosage form to break up in to granules of specified size (or smaller) under carefully specified conditions. ... In other words, DT (disintegration time) is measuring the breakdown of a dosage form and dissolution is measuring the drug being solubilized in the media.